Abstract
Tissue or developmental-specificity in central nervous system (CNS) represents strong functional diversity in high eukaryote genomes. Expression profile and sequence data become two major lines of information. In this paper, we conducted evolutionary analysis for the expression profiles of 14 gene families (57 genes) in vertebrate CNS development. We found the strong association between developmental profile and the gene family diversity. We speculate that gen(om)e duplication might be the evolutionary basis for functional diversity. This expression/sequence dual informatics approach is useful for tracking the genetic regulatory changes in complex biosystem.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
