Evolution of Post-Surgical Scars Treated with Pure Rosehip Seed Oil

Pedro Valerón-Almazán,Miguel A García-Bello,Anselmo J Gómez-Duaso,Néstor Santana-Molina,Gregorio Carretero

doi:10.4236/jcdsa.2015.52019

Pedro Valerón-Almazán, Miguel A García-Bello + Show 3 more

Open Access

https://doi.org/10.4236/jcdsa.2015.52019

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Abstract

The rosehip seed oil (RHO), obtained from different plant species of the genus Rosa, is one of the compounds used empirically for cosmetic improvement of skin scarring. Despite its widespread use in clinical practice, there are few studies evaluating the activity of this compound on the clinical course of cutaneous scars. The aim of this study was to determine the effect of Repavar&reg rosehip oil on improvement of post-surgical skin scars. One comparative, single-center, prospective clinical trial was carried out in 108 patients undergoing cutaneous surgery procedures in the Dermatology Service of University Hospital of Gran Canaria Dr. Negrín (Spain). Subjective parameters (erythema, discoloration, atrophy and hypertrophy) were evaluated at 6 and 12 weeks on 76 adults who treated scars with pure RHO twice a day (test group), 32 patients with not treatment (control group), and completed the study. Lesser degree of erythema was observed at 6 and 12 weeks in treated-patients compared with the control group and decreased discoloration and atrophy at 12 weeks, with statistically significant differences in all cases (p is useful for cosmetic improvement on erythema, discoloration and atrophyof post-surgical skin scars, getting a better overall evolution and appearance thereof.

Highlights

Healing is a natural and dynamic process in which body has to regenerate tissues after injury
A total of 160 patients were included in the trial, of whom 120 patients were treated with rosehip seed oil (RHO) and 40 underwent no treatment
103 patients from the 120 treated patients group attended the review of 6 weeks and 76 attended the review of the 12 weeks. 32 patients from the 40 patients control group went to the reviews at 6 and 12 weeks. 108 patients completed the study

Summary

Introduction

Healing is a natural and dynamic process in which body has to regenerate tissues after injury. This process develops along three phases, comprising inflammation, granulation tissue formation and maturation/remodeling [1]-[3]. Tissue enzymes remove excess of extracellular matrix and collagen, and remained fibrils are realigned along the tension lines. This remodeling process occurs during 6 - 12 months but may persist for years after initial injury [3]

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