Abstract
Porcine kobuvirus was first identified in early 2007 in Hungary. Originally thought to be confined to the intestine, almost 2 years later the virus was found in the blood of clinically healthy pigs on the same farm. Porcine kobuvirus may be widely distributed on pig farms worldwide.
Highlights
Porcine kobuvirus was first identified in early 2007 in Hungary
We report the endemic circulation and natural interhost evolution of porcine kobuvirus among domestic pigs on a pig farm within a 21-month period
This follow-up study indicates that domestic pigs are generally infected with porcine kobuvirus
Summary
The lowest rates of nucleotide mutations were seen in coding regions, L and 3D, respectively (Table 2). The highest changes in percentage within the 21-month period were found in 2C (1.49%), 2A (1.47%), and VP3 (1.34%) (Table 2). No amino acid changes were detected in regions VP1, 3A, and 3B. No cytopathic effect was seen in Vero cells after serial passages
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