Abstract
Charcot-Marie-Tooth disease (CMT) is the most common genetic nerve disorder. The most prevalent form, CMT1A, is characterised by demyelinating neuropathy with progressive foot and ankle weakness, contractures and deformity. The wide range of foot/ankle manifestations in CMT1A complicates the assessment, diagnosis and therapy. We aimed to characterise foot and ankle strength, flexibility, morphology and symptoms in children with CMT1A.
Highlights
Charcot-Marie-Tooth disease (CMT) is the most common genetic nerve disorder
1st Congress of the International Foot & Ankle Biomechanics (i-FAB) community Alberto Leardini, Chris Nester, Alex Stacoff and Dieter Rosenbaum Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1757-1146-1-S1-info.pdf
81 children aged 2–16 y with CMT1A were objectively assessed for strength with hand-held dynamometry [1], ankle dorsiflexion flexibility using the weight bearing lunge [2] and foot morphology with the Foot Posture Index (FPI) [3]
Summary
Charcot-Marie-Tooth disease (CMT) is the most common genetic nerve disorder. The most prevalent form, CMT1A, is characterised by demyelinating neuropathy with progressive foot and ankle weakness, contractures and deformity. Evolution of foot manifestations in children with Charcot-Marie-Tooth disease Joshua Burns*1, Monique M Ryan2 and Robert A Ouvrier1 Published: 26 September 2008 Journal of Foot and Ankle Research 2008, 1(Suppl 1):O5 doi:10.1186/1757-1146-1-S1-O5 1st Congress of the International Foot & Ankle Biomechanics (i-FAB) community Alberto Leardini, Chris Nester, Alex Stacoff and Dieter Rosenbaum Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1757-1146-1-S1-info.pdf
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