Abstract
To investigate the susceptibility pattern and the molecular epidemiology of Acinetobacter baumannii isolates in two periods (1994-1996 and 2004-2007) in Londrina University Hospital. Antimicrobial susceptibility of 150 A. baumannii isolates was assessed by disc diffusion and agar dilution methods. Genetic similarity amongst the isolates was evaluated by ERIC-PCR. Resistance of A. baumannii to carbapenems increased from 2% (1994-1996) to 73% (2004-2007). Thirty-eight clones were detected. The results of the study suggest that the high prevalence of carbapenem resistance amongst Acinetobacter baumannii organisms in this institution is not caused by the spread of a predominant clone. This work reinforces the importance monitoring antimicrobial susceptibility rates.
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