Abstract
The ethanol, chloroform and acetone extracts of five species from Acacia (Acacia albidia stems, Acacia mellifera aerial parts, Acacia nubica aerial parts, Acacia seyal var. seyal stems and Acacia tortilis aerial parts) were investigated for their antimicrobial activity against two standard bacterial strains of Gram +ve bacteria (Staphylococcus aureus (ATCC 25923)), Gram -ve bacteria (Pseudomonas aeruginosa (ATCC 27853)) and standard fungi Candida albicans (ATCC 90028) using the agar-plate well diffusion method. The chloroform extract was inactive compared to ethanol and acetone extracts. But ethanol extracts showed the maximum antimicrobial activity against the test organism. Amongst the plant species screened, ethanol extract of Acacia seyal stems showed maximum inhibitory activity (38 mm) and (37 mm) against Staphylococcus aureus and Candida albicans, respectively. The ethanol, chloroform and acetone extracts of Acacia mellifera (aerial parts) did not show any activity against the test organisms. Cholorophorm and acetone extracts via DPPH, the radical scavenging activities were found to be 91 ± 0.03, 88 ± 0.01 and 85 ± 0.04, respectively. The results of phytochemical screening showed that all extracts of studied plant contain flavonoids, saponins, terpenoids, steroids, alkaloids, phenols and tannins.
Highlights
According to World Health Organization medicinal plants would be the best source to obtain a variety of drugs
About 80% of individuals from developed countries use traditional medicine, which has compounds derived from medicinal plants
The aim of this study is to investigate the antimicrobial, antioxidant potentials and phytochemical studies of five species from Acacia to ascertain the rationale for its use in traditional medicine
Summary
According to World Health Organization medicinal plants would be the best source to obtain a variety of drugs. About 80% of individuals from developed countries use traditional medicine, which has compounds derived from medicinal plants. Such plants should be investigated to better understand their properties, safety and efficiency. For a long period of time, plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies [1]. Herbal treatment is one possible way to treat diseases caused by multidrug resistant bacteria. The use of plant extracts and phytochemicals, with known antibacterial properties, may be of immense importance in therapeutic treatments. In the past few years, a number of studies have been conducted in different countries to prove such efficiency [2]
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