Abstract
Sample preparation plays a pivotal role in enhancing the quality of analytical results by mitigating the complexity of samples. The evaluation and potential modification of extraction devices are paramount for achieving more efficient extraction processes and advancing the field of analytical chemistry. Tailoring extraction devices to specific applications often necessitates optimization, a topic explored in this review. Our review offers insights into innovative strategies for enhancing the structural aspects of extraction devices employed in chromatographic analysis. Crafting an efficient extraction device involves the meticulous optimization of multiple variables, encompassing the choice of extraction phases and binders, device shape and geometry, and operating conditions. This comprehensive examination delves into the underlying principles that govern the design optimization of extraction devices for diverse applications. Moreover, the knowledge imparted herein serves as a valuable resource for scientists seeking a deeper understanding of extraction principles and their broader implications, transcending specific fields of study. By harnessing these insights, researchers can propel the frontiers of analytical chemistry toward more accurate and effective sample preparation methodologies.
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