Abstract
Introduction : Malignen change in dermatofibrosarcoma protuberans is a rare phenomenon. We present one case. Case report : a patient operated for local recurrences of dermatofibrosarcoma. The histopathological study showed a fascicular and highly cellular histological pattern in the dermis, with importante mitotic activity.Sometimes the nucleus was central chow small indentations produced by multiple small vacuoles like a lipoblast, with an extensive capillary network apparence the diagnosis of liposarcoma was proposed. Discussion : malignen change of dermatofibrosarcoma is defined by its herringbone architecture, hypercellularity, and increased mitotic rate .Occasionally, can lead to misdiagnosis with other spindle-cell tumors especially liposarcoma which has a worse prognosis. Multiple sampling and immunohistochemistry with antibody CD34 help to establish the right diagnosis. Conclusion: The degree of aggression is related to the histological grade and of sarc omatous transformation. The prognosis of the transformed dermatofibrosarcoma is more aggressive than the classic than one in liposarcoma.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
