EVOLUCIÓN A UN AÑO DE LOS EFECTOS ADVERSOS, EN UNA COHORTE DE PACIENTES CON IMPLANTE SUBDÉRMICO DE DESOGESTREL

Abstract

SUMMARY Objective: To determine the adverse effects of implants subskin of desogestrel. Method: A descriptive longitudinal study was made in a cohort carrying patients of implants that they had as minimum three months of use, previous informed consent were included in the study. Four measurements were made in quarterly form, registering the most frequent effects, referred by the patient. It was used descriptive statistic and confidence intervals. Results: It was study 50 patients. The presented effects with greater percentage in the first trimester were: alterations of cycle 48%, mastalgia 46%, amenorrhoea 40%, dizzies 40%, headache 40%, nauseas 30%, acne 28%, increase of weight 26% and local pain 10%. It was observed at the end of the third quarterly reduction of the statistically significant effects of the headache, mastalgia, dizzies (p<0.05), for the fourth trimester nauseas and alterations of the cycle (p<0.05). The 11.1% of the patients deserted of the method at the end of the study. It was observed that the use of desogestrel had a significant statistic for the control of the dismenorrea with p< 0.05 at the end of the fourth trimester of use. Conclusions: You implant them of desogestrel have adverse effects important in the first’s months of use to diminish most of them at the end of the first year.