Evidence that hidden hearing loss does not vary systematically as a function of noise exposure in young adults with normal audiometric hearing

Abstract

Cochlear synaptopathy, or “hidden hearing loss,” refers to a loss of synapses between inner hair cells and auditory nerve fibers, and is observed in rodent models as a consequence of noise exposure and/or aging. In humans, cochlear synaptopathy is not thought to be detectable by pure tone audiometry, as thresholds to soft sounds in the rodent models are not permanently elevated. One hundred and forty audiometrically normal participants below the age of 35 and with a range of lifetime noise exposures performed an extensive battery of tests, including electrophysiological measures, psychophysical tests, and speech-in-noise tests. Inter-aural phase discrimination, amplitude modulation detection, and spatial release from masking on a speech task were found to be sensitive to noise exposure; however, these trends are weak and only the phase discrimination task followed the predicted direction (i.e., high noise exposed individuals showing elevated thresholds). None of the electrophysiological measures, including wave I of the ABR, showed a strong relation with noise exposure. The results suggest that either: (i) hidden hearing loss is not prevalent in young normally hearing adults, or (ii) even listeners with comparatively low levels of noise exposure have the disorder and that there is no additional consequence of high levels of exposure.