Evidence of Dental Lamina Preservation in the Development of Mice First Molars

Hermes Pretel,Sebastião Hetem,Marlei Seccani Galassi,Celina Antônio Prata,Lizeti Toledo Oliveira Ramalho

doi:10.31487/j.dobcr.2021.01.01

Abstract

The aim of this work was to analyse the behaviour of the dental lamina during the development process of first molar teeth. The offspring of female mice were analysed at the 16th day of intra-uterine life and since birth till 17 days old with the aim to evaluate the dental lamina evolution of upper and lower first molars. The animals were sacrificed, and the heads embedded in paraffin in order to get frontal or sagittal sections whose were stained by hematoxylin and eosin method. The results showed a very clear presence of the dental lamina in all periods under analysis, without the occurrence of its disorganization, in other words, it was permanently connecting the developing tooth germ to the oral epithelium until advanced dental eruption.

Highlights

The analysis of dental lamina evolution have brought some misunderstanding once that many have been the descriptions of its destiny and there is some confusion when it is related to deciduous or permanent teeth
As it can be seen in the literature, while for some authors the dental lamina undergoes a small disintegration process but never disappears, for the deciduous teeth for other authors there is a gradual loss of its structure, rupture of its continuity and invasion by the connective and bony tissues disposed between the tooth germ and the lining oral epithelium with separation and insulation of developing tooth germ [1,2,3,4]
*Correspondence to: Hermes Pretel, D.D.S., M.Sc., Ph.D., Department of Restorative Dentistry, Araraquara School of Dentistry, São Paulo State University Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Rua Humaita 1680, Araraquara, São Paulo, 14800-901, Brazil; Tel: +551633016520; E-mail: hpretel@hotmail.com differentiation in its surface and the establishment of dental sac structures whose were interrupted at the dental lamina level

Summary

Introduction

The analysis of dental lamina evolution have brought some misunderstanding once that many have been the descriptions of its destiny and there is some confusion when it is related to deciduous or permanent teeth As it can be seen in the literature, while for some authors the dental lamina undergoes a small disintegration process but never disappears, for the deciduous teeth for other authors there is a gradual loss of its structure, rupture of its continuity and invasion by the connective and bony tissues disposed between the tooth germ and the lining oral epithelium with separation and insulation of developing tooth germ [1,2,3,4]. The aim of this paper is to verify the fate of the dental lamina, its period of persistence in teeth without successor teeth and evaluate what happens with the dental lamina of permanent teeth whose have deciduous predecessors as a review of what is described in the literature

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Results

Conclusion