Evidence of Anaplasma spp. exposure in native Korean goats (Capra hircus coreanae)

Abstract

Anaplasmosis in animals is caused by Anaplasma spp. including A. phagocytophilum, A. marginale, A. centrale, A. ovis, and A. bovis, which are obligate intracellular rickettsial pathogens transmitted by ticks. Infection in animals is considered an important constraint on livestock production. In Korea, the prevalence of Anaplasma spp. has been investigated in several species, including cattle, dogs, and rodents, but there are no available data on anaplasmosis in goats. The purpose of this study was to investigate the presence of Anaplasma spp. in native Korean goats (Capra hircus coreanae) using a commercial competitive ELISA which specifically detects antibodies against A. marginale, A. centrale, and A. ovis. A total of 36 (6.6%) of 544 goat serum samples tested seropositive for Anaplasma spp. With regard to age, 4.9% (7/144), 9.5% (27/283), and 1.7% (2/117) of samples tested seropositive in the young (< 1 year), adult (≥ 1 year), and unknown age groups, respectively, with significant differences among groups (P < 0.05). The seroprevalence by region was 1.7% (2/121), 2.6% (2/77), and 9.2% (32/346) in the northern, central, and southern regions, respectively, with significant differences among regions (P < 0.05). With regard to the season of sample collection, 3.3% (4/122) and 7.6% (32/422) samples tested seropositive during the cold and warm seasons, respectively. To the best of our knowledge, this is the first known study reporting the seroprevalence of Anaplasma spp. in native Korean goats. Despite the relatively low prevalence of Anaplasma spp. in native Korean goats compared with that in animals from other countries, these results should not be disregarded because infection with Anaplasma spp. in animals has long been recognised, and the potential for horizontal transmission cannot be excluded.