Evidence for the existence of a substance P-containing pathway from the nucleus laterodorsalis tegmenti (Castaldi) to the lateral septal area of the rat

Abstract

The existence of a long ascending substance P (SP)-containing neuron system from the nucleus laterodorsalis tegmenti of Castaldi to the lateral septal area was demonstrated in this study. The destruction of the n. laterodorsalis tegmenti resulted in a marked reduction of SP-positive fibers in the ipsilateral lateral septal area.