Abstract
Localized irradiations of hair follicles of mice, made possible by short- range heavy ions from a heavy ion linear accelerator and by collimated narrow slft beams of accelerated electrons, demonstrafe depigmentation effects remote from the site of original irradiation damage and also depigmentation effects delayed until the second hair growth following irradiation. To explain these indirect effects, the tentative hypothesis is again proposed that suggests that the upper permanent external sheath is the true germ. It produces the new lower external sheath and bulb of each hair generation, and damage from irradiation causes it to fail in fts capacity of incorporating and culturing the potential melanocytes which are present primarily in the dermal papilla or the resting epithelial tab conventionally called the germ. In any case, with respect to pigmentation and melanocytes, there are indirect effects of irradiation. (auth)
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