Abstract

By inducing developmentally regulated dose-dependent cardiovascular, renal, and endocrine effects, dopamine (DA) increases blood pressure (BP) and urine output in the hypotensive and/or oliguric neonate (Seri I, J Pediatr 126:333-344, 1995). In adults, the drug-induced selective renal and mesenterial vasodilation contributes to the beneficial effects of DA. However, no study has confirmed the presence of these selective vascular dopaminergic effects in neonates.

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