Abstract

In a study of a cycloheximide-resistant mutant of the oomycete Achlya bisexualis Coker & Couch two important observations have been made. The first concerns the inheritance of cycloheximide resistance and the second is the position of meiosis in the life cycle of this organism. Induced cycloheximide-resistant mutants are known in several species of fungi. The inheritance of cycloheximide resistance in Saccharomyces cerevisiae Hansen was shown to be controlled by six genes, four of which were dominant and two recessive (Wilkie and Lee, 1965). Additional modifier genes were also hypothesized. In both Physarum polycephalum Schw. (Haugli et al., 1972) and Neurospora crassa Shear & Dodge (Hsu, 1963) resistance was shown to be controlled by two loci. In

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