Abstract
INTRODUCTION: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. AIM: We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019. METHODS: WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq. RESULTS: Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. CONCLUSIONS: Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.
Highlights
Aim: We report the first case of West Nile virus (WNV) infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state
WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq
Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005
Summary
Abstract Introduction: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. Aim: We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state.
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