Abstract
AbstractThe presence of phosphoenolpyruvate carboxykinase (PEPCK) activity in the direction of oxaloacetate formation in Rana ridibunda erythrocytes was detected. In addition, the levels of all the individual enzymes leading from phosphoenolpyruvate (PEP) to succinate production have been determined in Rana ridibunda hemolysates. Incubation of the intact red cells in the presence of the PEPCK activity inhibitors, quinolinic, and mercaptopicolinic acid resulted in the inhibition of the succinate levels whereas the pyruvate levels were increased. The flow of carbon through PEPCK indicates its participation to an alternative route of PEP metabolism with the advantage of two additional molecules of adenosine triphosphate (ATP) production per glucose molecule catabolized. The possible mechanisms that could control the flow of PEP either towards pyruvate or towards oxaloacetate in Rana ridibunda erythrocytes are discussed. © 1993 Wiley‐Liss, Inc.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
