Abstract
In order to elucidate the role of the adrenergic nervous system in the mechanism of TSH release in men the effects of alpha- and beta-receptors blocking agents were studied in 11 healthy volunteers. Phentolamine administered iv as a bolus injection in a dose of 10 mg, significantly lowered the TSH release in basal condition and in response to TRH stimulation. However, propranolol in a dose of 0.1 mg/kg administered in the same fashion as phentolamine had no effect on the TSH secretion. The results obtained suggest that the alpha-receptors of the adrenergic system are involved in the physiological mechanism which stimulates TSH release in men.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
