Abstract

The World Health Organization (WHO) has produced guidelines for the management of common illnesses in hospitals with limited resources. This series reviews the scientific evidence behind WHO's recommendations. The WHO guidelines and more reviews are available at: http://www.ichrc.org The WHO Pocketbook of Hospital Care for Children [1] recommends in necrotizing enterocolitis to stop enteral feeds, pass a nasogastric tube, start an intravenous (IV) infusion and give ampicillin plus gentamicin plus metronidazoloe for 10 days (p. 57) This review addresses the question: For young infants with suspected necrotizing enterocolitis (NEC), what is the effectiveness of different parenteral antibiotic regimens in preventing progression and sequelae?

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