Abstract
The Guideline Development Subcommittee of the AAN conducted a literature search and review of 10 Class I or Class II trials of treatment for parenchymal neurocysticercosis.
Highlights
Investigators at Universities of Barcelona, Pennsylvania, Oviedo, and Valencia, and the Spanish NMDAR Encephalitis Work Group report the clinical features of 20 pediatric patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis seen in a single center in Spain in the last 4 years
Initial symptoms were neurologic in 12 (60%) and psychiatric in 40%
Ovarian teratoma was identified in 2 patients (10%), 1 at disease onset and the other one-year later
Summary
An extremely low-dose ACTH step-up protocol is used to treat West syndrome (WS) in this institution (Oguni H, et al Brain Dev 2006 Jan;28(1):8-13). At 1 year or more follow-up, 13 patients (48%) remained seizure-free. This ACTH extremely low-dose step-up method achieved 61% short-term and 48% long-term remission, without significant side effects.
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