Abstract
Methods: Research was conducted using self-experience along with scientific literature findings to fully understand the physical and emotional syndromes of premenstrual dysphoric disorders (PMDD). Findings: Correlation with low progesterone in relation to negative affective and physical symptoms during the follicle and luteal phase were observed. Allopregnanolone, a neurosteroid, as a therapeutic agent can alleviate PMDD symptoms. Specific nutritional sources can also help alleviating the presenting symptoms. Conclusion: Awareness about PMDD symptoms is warranted in women experiencing them. Providers need to be familiar of the emotional and physical effect of low progesterone and the mechanism of action of Allopregnanolone in treating PMDD, when other interventions such as psychotherapy and other pharmacological intervention failed.
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