Abstract
The Technical Committee on Biomedical Acoustics is one of the most diverse groups in the Acoustical Society of America. It is comprised of individuals whose interests cover a broad range of diagnostic and therapeutic applications or, more generally, the interaction of sound with biological materials. Exciting new developments in diagnostic ultrasound include innovative contrast agents and “dual-wave” imaging, examples being shear wave elastography, acousto-optic and opto-acoustic imaging. Therapeutic applications are expanding beyond lithotripsy and the treatment of tumors via thermal ablation. Mechanical ablation of soft tissue, known as histotripsy, is an area of active research. Transcranial magnetic resonance guided focused ultrasound is being used for the non-invasive treatment of various brain disorders, including essential tremor, neuropathic pain, and Parkinson’s disease. The ability to temporarily open the blood-brain barrier and deliver chemotherapy to brain tumors using focused ultrasound has been demonstrated in a human for the first time. Researchers are also developing echogenic liposomes and microbubbles for targeted drug and gene delivery using low intensity focused ultrasound. As technology and protocols continue to evolve, developments in biomedical acoustics hold considerable promise towards the advancement of both diagnosis and treatment of debilitating diseases.
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