Abstract
Event-related-potential (ERP) markers of traumatic brain injury (TBI) severity and cognitive function – Understanding how the brain works and thinks post TBI
Highlights
Three key features influencing traumatic brain injury (TBI), management and rehabilitation outcomes are; a) psychiatric post-TBI sequelae, b) neurological and neuropsychiatric post-TBI sequelae and c) other injuries co-existing with TBI
Individuals with alcohol-related disorders post-TBI showed generalized brain atrophy, reduction in prefrontal cortical (PFC) volume and EEG studies revealed changes in their event-related potential (ERP) patterns; these patterns returned to no-alcohol-consumption post-TBI patterns if individuals observed abstinence from alcohol (28-30)
In instances where impairments require more sensitive and fine-grained tests using EEG and event-related potentials (ERPs) could provide an endogenous viewpoint of cognitive processes and changes in cortical function, aspects that imaging cannot capture. In this context the present paper examines if domain- and symptom-based EEG and ERP markers of cognitive-impairments or TBI-severity using EEG machines like NeuralScan by Medeia would be a more appropriate approach
Summary
Event-related-potential (ERP) markers of traumatic brain injury (TBI) severity and cognitive function – Understanding how the brain works and thinks post TBI. Miranda P1, Christopher D Cox, Alexander M1, Danev S3 and Jonathan RT Lakey1* 1Department of Surgery and Biomedical Engineering, University of California Irvine, California, USA 2Department of Neurology, David Geffen School of Medicine, University of California, LosAngeles, California, USA 3Medeia Inc, Santa Barbara, CA, USA
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