Abstract

Trials of anticoagulants for stroke prevention generally involve patients with frequent and symptomatic atrial fibrillation (AF); however, the growing population of patients with implanted cardiac devices has enabled the detection of subclinical AF. The manufacturer-sponsored ASSERT trial in patients with a dual-chamber pacemaker or implantable cardioverter-defibrillator was designed to evaluate whether a special pacing algorithm would prevent AF and whether …

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