EVALUTION OF RISK FACTORS AND SEROPREVALENCE RATE OF TOXOPLASMOSIS IN THE ELDERLY

Abstract

Toxoplasmosis is an infection caused by the protozoan Toxoplasma gondii, whose definitive hosts are cats and whose intermediate hosts include humans.This research aims to evaluate aspects related to seroprevalence rates of anti-T. gondii antibodies among elderly users of the Primary Health Care Service in the municipality of Aparecida de Goiânia, state of Goiás, Brazil. A total of 101 elderly people participated in the study, and a questionnaire was applied to examine sociodemographic factors related to risk factors for toxoplasmosis. Five ml of peripheral blood were collected from all the participants for serological tests. IgM and IgG antibody screening was performed using the ELISA technique. The average age of the participants was 69.5 years, the seroprevalence rate was 75.2% (76/101) of IgG (+), and 24.8% (25/101) were non-reactive. IgM and IgG antibodies were found in 2.9% (3/101) of the participants. An IgG avidity test was performed, which revealed that the antibodies in the three samples were of low avidity, thus indicating that these individuals were in the acute phase of the infection. It was concluded that, in terms of socioeconomic conditions, an income of one to three monthly minimum salaries is the predominant risk factor for toxoplasmosis in this group.