Abstract
The leaves of some plants are flamed and used to dress injured skin, to stimulate healing and to ward off infection. This study aims to determine antioxidant activities of Plantago lanceolata L., Plantago major L. ssp. major, Rubus hirtus Waldst& Kit., Sambucus ebulus L., Morus alba L. and Hedera helix L., which grown in Duzce and its surroundings and are used for anti-inflammatory purposes, and especially for wound-healing. The total phenolic compound of these plants was also evaluated. In order to determine the antioxidant compounds and antioxidant capacity of these plants, different in vitro methods. Resulting from our study, while P. lanceolata, R. hirtus, S. ebulus and P.major ssp. major had similarities in terms of phenolic compounds content, M. alba and H. helix were found to have relatively low content of phenolic compounds. In general, Plantago species and R. hirtus showed high antioxidant activities.
Highlights
It has been established that oxidative stress is among the major causative factors in induction of ageing and immunosupression, and many chronic and degenerative diseases including atherosclerosis, ischemic heart diseases, diabetes mellitus, cancer, neurodegenerative diseases and others [1]
Determination of total phenolic content, DPPH and dimethyl-p-phenylenediamine dihydrochloride (DMPD) radical scavenging, cupric ion (Cu(2+)) reducing, inhibition lipid peroxidation, hydroxyl radical scavenging capacity were applied to the plants which are collected from Düzce and its surroundings and used as folk medicine
The highest amount was found in the P. lanceolata, followed by R. hirtus, S. ebulus, P. major ssp. major, H. helix and M. alba, respectively
Summary
It has been established that oxidative stress is among the major causative factors in induction of ageing and immunosupression, and many chronic and degenerative diseases including atherosclerosis, ischemic heart diseases, diabetes mellitus, cancer, neurodegenerative diseases and others [1]. Natural antioxidants can protect the human body from free radicals and retard the progress of many chronic diseases as well as retarding the lipid oxidative rancidity in foods [2]. Recent studies have investigated the potential of plant products as antioxidants against various diseases induced by free radicals [3]. Plantago lanceolata and Plantago major are species of Plantago genus including 275 species throughout the world Their leaves are used as astringent, anti-inflammatory, expectorant, topical anodyne, antibacterial, styptic, hemoptysis, hematuria, sore throats, coughs, diarrhea, dysentery, hemorrhoids, cervicitis, rectal fissures, insect bites, snake bites, cuts, bruises and abscess. These Plantago sp. consist several compounds, including iridoid glycosides (aucubin, catapol, gardoside, geniposidic acid, mayoroside, melittoside), terpenoids (loliolid, ursolic acid, oleanolic acid), caffeic acid derivatives (caffeic acid, chlorogenic acid, plantamajoside R, aceteoside R), polysaccharides (plantaglucide, glucomannon, PMII, PMIa), alkoloids (indicain, plantagonin), polyholozide, flavonoids and flavone glucosides (luteolin-7 glucoside, hispidulin 7-glucuronide, apigenin, balcalein, scutallarin, plantagonin) [6]
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