Abstract
Objective To compare basic cognitive capability teat (version 2.0) with the method recommended by ISPOCD (international study of postoperative cognitive dysfunction) on the evaluation of postoperative cognitive dysfunction (POCD) in elderly patients, and study the correlation of two different methods. Methods Two neuropsychological tests were performed preoperatively, and postoperatively on Day 7 and 3 months upon 131 elderly patients undergoing elective major non-cardiac surgery and 30 healthy elderly volunteers that were set as a control group. One was Basic Cognitive Capability Test (Method A), including digit copying (A1), mental arithmetic (A3), et al. However, The other was recommended by ISPOCD (Method B), including trail making test (B1), digit symbol sub-test (B2), et al. Z score was used to analyze the data. POCD was defined as Z score ≥2. Results (1) 120 out of 131 patients had completed the tests on Day 7 postoperatively, and then 67 among them had finished the tests 3 months postoperatively. (2) The incidence rate of POCD on Day 7 was (12.5% and 10.8%,P>0.05); and at 3 months was (5.97% and 7.46%, P >0.05). (3) Two methods were consistent for evaluation of POCD on Day 7 and 3 months postoperatively. Kappa were 0. 758 and 0.881, P<0.05. (4) Both on Day 7 and 3 months, the combined Z score of Method A and Method B had significant correlation, r =0.316 and 0.302 ,P < 0.05. (5) As for speed of recognition, digit copying (A1) vs. trail making test (B1) had significant correlation, r=0.517, P<0.05. For ability of study and performance, mental arithmetic (A3) vs. digit symbol subtest (B2) had significant correlation, r = 0. 52, P < 0. 05. Conclusion Basic cognitive capability test was consistent with tests recommended by ISPOCD for evaluation of POCD. Basic cognitive capability test using computer was more objective, accurate and beneficial for clinical practice. Key words: POCD; Basic cognitive capability test; Neuropsychological tests
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