Abstract
Recently, CuInS2 quantum dots (CIS QDs) are extensively applied in biological applications because of their distinctive optical property. These novel ternary semiconductor CIS QDs can be developed into good biomarkers or trackers because they do not contain cadmium, unlike CdTe and CdSe QDs with high risk for cytotoxicity. However, reports on toxicity and effective factors affecting CIS QDs are seldom developed, and in vivo chemical stability has not been clearly investigated. In this study, we focused on the fate, degradation, and exposure time of CIS QDs in Caenorhabditis elegans (C. elegans), which is used as a model organism in biology. Moreover, X-ray absorption near-edge structure (XANES) is used to identify the oxidation state of CIS and CIS/ZnS QDs in various exposure times. The purpose was to use different oxidation states of copper and zinc ions of QDs to achieve chemical stability in C. elegans. CIS and CIS/ZnS QDs were synthesized by hydrothermal method, and QDs were transferred to aqueous sol...
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