Evaluation value of non-HDL-C and AI in patients with coronary heart disease

Abstract

Objective To investigate the assessment value of non high density lipoprotein cholesterol (non-HDL-C) and atherosclerosis index (AI) in patients with coronary heart disease. Methods One hundred patients with CHD were divided into acute myocardial infarction group (33 cases), unstable angina group (38 cases) and chronic coronary heart disease group (29 cases), and 100 cases health check cases over the same period examination were selected as the control group. The general data such as gender, age, body mass index, blood glucose, smoking history, long-term drinking history, and past medical history, and biochemical indicators such as blood glucose, serum total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), serum creatinine (Cr), triglycerides (TG), liver function, blood uric acid were compared among the four groups. Results In the acute myocardial infarction group, unstable angina group and chronic coronary heart disease group, the age, TG and uric acid levels were significantly higher than those in the control group (P<0.05); compared with chronic coronary heart disease group, the body mass index, pressure, blood glucose, TC, TG, HDL-C, LDL-C level, liver functionnon, HDL-C and AI had significant differences in patients with acute myocardial infarction group and contraction of unstable angina group (P<0.05); compared with the acute myocardial infarction group and unstable angina group, systolic blood pressure and liver function had significant differences (P<0.05). There was negative correlation of non-HDL-C with age (P<0.05), and there was positive correlation of non-HDL-C with LDL-C, TC and TG (P<0.01); AI was significantly negatively correlated with age and HDL-C (P<0.05), and positively correlated with LDL-C, TC, TG (P<0.01). Conclusions Non-HDL-C and AI levels in patients with acute myocardial infarction were significantly higher in patients with chronic coronary heart disease group. It has an important significance in evaluation of non-HDL-C and AI levels on patients with coronary heart disease. Key words: Non-high density lipoprotein cholesterol; Atherosclerosis index; Coronary heart disease; Value evaluation