Abstract
COVID-19 is a new coronavirus that has the potential to be deadly. The World Health Organization (WHO) has declared the COVID-19 outbreak to be an international public health emergency. According to new evidence, comorbid diabetes in COVID-19 patients is linked to disease progression and even death. Aim of study is to evaluate the role of serum osteopontin, CRP and D-Dimer activity in the severity of covid19 and possibility of using these biomarker as predictors for mortality of covid19 in diabetic patients. This is a cross sectional, hospital based study. This study was carried out from 1st December 2021 to 30th January 2022 and included 60 Patients admitted to COVID19 isolation centers in Alshefa-14 and Kirkuk general hospital (30 COVID-19 without D.M and 30 COVID-19 with D.M) and 30 control samples. All data were collected through a face-to-face interview by a questionnaire. The current study showed a significant increase in all the measured parameters in patients with positive COVID-19 when compared to control group with no apparent clinical diseases. D-dimer increased in patients by a mean of (3215 ng/l, SD ± 50) when compared to control group (218 ng/L SD ± 27.3) with (p-value <0.05).
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