Evaluation on therapeutic effect of needle warming moxibustion combined with Banxia-Xiexin decoction in diabetic gastroparesis

Abstract

Objective To investigate the effect of warm acupuncture combined with Banxia-Xiexin decoction on diabetic gastroparesis (DGP). Methods A total of 86 DGP patients who met the selected criteria were divided into two groups by random number table method. The control group was treated with warm acupuncture. The observation group added Banxia-Xiexin decoction on the basis of the control group. Both groups were treated for 4 weeks. The clinical efficacy of motilin (MTL), somatostatin (SS) and leptin (LP) were evaluated by ELISA. Results The total effective rate of the observation group was 97.7% (42/43) and the control group was 88.4% (38/43). The difference between the two groups was statistically significant (χ2=9.492, P<0.01). The post-treatment serum MTL (340.82 ± 51.32 ng/L vs. 422.42 ± 64.51 ng/L, t=43.184) and LP (1.98 ± 0.24 ng/ml vs. 2.78 ± 0.27 ng/ml, t=5.330) of the observation group were significantly lower than those of the control group (P<0.01), while the serum SS (47.62 ± 7.48 ng/L vs. 33.26 ± 5.09 ng/L, t=8.494) was significantly higher than that of the control group (P<0.01). Conclusions The warm acupuncture combined with Banxia-Xiexin decoction can obviously relieve the clinical symptoms of DGP patients, reduce the level of leptin, and there is no obvious adverse reaction. Key words: Needle warming therapy; Diabetic gastroparesis; Banxia-Xiexin decoction; Leptin