Evaluation on adequacy of hemodialysis by on-line clearance monitoring and Kt/V of Correlation Analysis

Abstract

Objective To evaluate the adequacy of hemodialysis by online clearance monitoring (OCM) and Kt/V of correlation analysis.Methods The Kt/V values of 48 maintenance hemodialysis patients in the Department of Nephrology of General Hospital of PLA were accessed by both OCM of Germany BeiLang Dialog + hemodialysis machine and single-pool urea kinetic model.The Kt/V calculation value was also checked by the urea dynamics - room variable volume model.The results generated at different time point were compared,including at the real time,before and after appearing through blood by On - line Clearance Monitoring,and correlation analysis of Kt/V value was performed.Results There was no significant difference on evaluating the level of Kt/v by these two methods.The relationship between the results of the two methods was significantly positive related.(r=0.539,P ＜ 0.01).Conclusions During hemodialysis,the OCM option provides an accurate tool for continuous on-line monitoring of urea clearance. Key words: Urea/AN; Renal dialysis