Abstract
Background: Teucrium polium a member of Lamiaceae family is a widely used plant in Algerian traditional medicine; however, there are few reports on its use as a healing agent. The aim of this study is to investigate the wound healing property of aerial part of this plant on excisional wounds. Methods: Twenty adult male Wistar rats with an average weight of 180 g were used in this study. Post wound development, 10 rats received daily treatment with the plant ointment and the remaining rats served as control. Measurement of wound areas and calculation of closure percentages were made in order to evaluate wound healing macroscopically and a sample of the scar tissue formed was submitted at day 24 post treatment for a histological study. Result: Better and faster healing was observed in the Teucrium polium group compared to control. This improvement in wound healing was confirmed by the histological study which revealed that the effect of the plant lies in its stimulation of proliferative phase and its regulation of the inflammatory phase of wound healing. Based on these results, we could deduce that Teucrium polium enhance healing of excisional wounds.
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