Evaluation of utilised doses of Heart Failure (HF) medications between genders and its association with clinical status among Heart Failure (HF) patients at hospital Serdang

Abstract

Objective This study aimed to evaluate the utilised doses of HF medications between genders among HF patients in local setting. Methods This study was conducted as retrospective study involving data collection from medical records of patients with documented HF in Hospital Serdang, Selangor. A total of 131 patients (74 males versus 57 females) were conveniently recruited from patients undergoing follow-ups at cardiology outpatient clinic, Hospital Serdang, Selangor with matched age, different ethnics, baseline and current EF and comorbidities. Utilised doses of HF medications were categorised as percentage of recommended doses or usual daily doses, which were 0%, <50%, ≥50% and ≥100%.Results No significant difference was observed in utilised doses of HF medications between genders in study population which proved that the utilised doses of HF medications were not influenced by gender differences. However, Malay and Indian were found to utilise higher MRA doses compared to Chinese and indigenous people (P < 0.05). This study also found that baseline (r = -0.386; P < 0.001) and current (r = -0.265; P < 0.01) ejection fraction were weakly and inversely correlated with MRA utilised doses.