Evaluation of urodynamics parameters in different age and incontinence group of women

Abstract

Aim: Overactive bladder syndrome (OAB) is known to have a negative impact on quality of life, and cause discomfort daily. Population-based studies on females report a prevalence of OAB which varies between 9.7% and 35.7%, with a substantial rise with increasing age. The primary aim of this analysis was to assess whether age was associated with differences in urodynamic testing parameters, using age as a continuous variable, and comparing women within wider age groups to understand physiologic variation. Methods: In this retrospective cohort study, we evaluated the patients who were admitted to the Department of Gynecology and Obstetrics Department of Istanbul Education and Research Hospital between January 2017 and January 2020 with lower urinary tract symptoms (LUTS). Results: We found that age, first sensation and first desire to void were strongly correlated (P=0.007, P=003 respectively), but a strong desire to void and maximum cystometric capacity were not (P=0.09, P=0.11 respectively). There was a weak negative correlation between detrusor pressure (Pdet) and age (p=0.08). Histogram analysis of bladder compliance among stress, urge, mix incontinence and normal patients revealed that maximum compliance occurred in women of reproductive age. Conclusion: Aging is associated with decreased self-control, thus, increased prevalence of LUTS symptoms among older women might be more accurately considered as the loss of an adaptive threshold to urinary control rather than age-associated decline in urinary functions.