Abstract

To evaluate the effects of bupivacaine 0.5 and 0.25% in intravenous regional anesthesia (IVRA) and brachial plexus block (BPB), respectively, on anesthesia, motor block and cardiovascular parameters in dogs. Fourteen healthy adult dogs averaging 10 kilograms (kg) of body weight. Animals were randomly assigned to receive one of the two treatments IVRA (n=7) or BPB (n=7). All the animals were sedated with acepromazine (0.1 mg/kg intramuscular). To execute the BPB was used an electrical nerve stimulation. Anesthesia, motor block, sedation, cardiovascular and respiratory effects were measured as effect of the treatment. BPA showed superior efficiency and duration of anesthesia (BPB - 456 +/- 94 minutes vs IVRA - 138 +/- 44) as well as motor block. There only physiologic parameter which change were the systolic pressure in BPB and respiratory rate for both treatments. In dogs the 0.25 % hyperbaric bupivacaine in BPB produces a front limb anesthesia about three times more than the 0.5 % in IVRA, with ptosis of the limb blocked and little interference in the cardiovascular system but with decrease in respiratory rate.

Highlights

  • The inhalatory or venous general anesthesia is not applied for many patients who need surgery in front limbs

  • The aim of this study was to evaluate the bupivacaine effects on intravenous regional anesthesia (IVRA) and brachial plexus block (BPB) on anesthesia, motor block and cardiovascular parameters in dogs. This experiment was approved by the Ethic Commission of Animal Utilization (CEUA) from the Federal University of Mato Grosso do Sul, (UFMS), so that it agrees with the ethic principles of Brazilian College of Animal Experimentation

  • Dogs were randomly allocated to two different groups with 7 animals each being BPB and IVRA using of 0.25 % (3.0 mg/kg; mean dose 10 mL) and 0.5 % (0.5 mg/kg; mean dose 4 mL), respectively of bupivacaine plus glucose (5 mg + 80 mg/mL, respectively) without epinephrine

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Summary

Introduction

The inhalatory or venous general anesthesia is not applied for many patients who need surgery in front limbs It is due, because some alterations as pregnancy, age, obesity and pathologies involving the renal, pulmonary or hepatic systems can limit the utilization of these anesthetic methods. The main blocks in front limb surgeries bellow the scapula-humeral articulation are the brachial plexus block (BPB) and intravenous regional anesthesia (IVRA). These techniques are sub utilized because, as in BPB, the anesthetics being deposited with

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