Abstract

Background:Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement.Materials & methods:We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex amplitude with an iPhone pupillometer and a portable infrared pupillometer. We then enrolled 40 additional subjects and made serial measurements with each device.Results:Failure occurred in 30% of attempts made with the iPhone pupillometer compared with 4% of attempts made with the infrared pupillometer (Fisher’s exact p = 0.0001). Method comparison of the two devices used simultaneously showed significant disagreement in dynamic measurements.Conclusion:The iPhone pupillometer had poor repeatability and suggests that it is not a practical tool to support clinical decisions.

Highlights

  • Pupillometers have been proposed as clinical assessment tools

  • Accurate portable instruments are recommended for ease of use and convenience

  • Infrared portable pupillometers have been in use for over 20 years and have been tested for accuracy

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Summary

Introduction

Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement. Materials & methods: We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex amplitude with an iPhone pupillometer and a portable infrared pupillometer. We enrolled 40 additional subjects and made serial measurements with each device. Results: Failure occurred in 30% of attempts made with the iPhone pupillometer compared with 4% of attempts made with the infrared pupillometer (Fisher’s exact p = 0.0001). Method comparison of the two devices used simultaneously showed significant disagreement in dynamic measurements. Conclusion: The iPhone pupillometer had poor repeatability and suggests that it is not a practical tool to support clinical decisions

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