Abstract
Background: Total tumour volume is predictive factor for hepatic resection in some solid tumours, but its significance in colorectal liver metastases has not been fully investigated. liver is most frequent location of distant metastasis for colorectal cancer, which is 1 of most common cancers to cause cancer-related deaths globally. For colorectal liver metastases, hepatic resection is widely recognized as most effective therapy & only possibly curative operation. assessment of tumour burden can depend significantly on total tumour volume. Aim: In this review, we sought to assess the total tumour volume decrease ratio in colorectal liver metastases that were initially unresectable following 1st-line therapy, Summary: After receiving 1st-line systemic therapy, decreased ratio of TTV had been reliable predictor of conversion result & long-term prognosis in studied cases with originally unresectable CRLM.
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