Evaluation of Total Antioxidant Capacity of Saliva in High School Students.

Mahmoud Rahmani,Vahideh Ghorchi,Fatemeh Rezaei,Asad Vaisi-Raygani

doi:10.5539/gjhs.v8n4p89

Mahmoud Rahmani, Vahideh Ghorchi + Show 2 more

Open Access

https://doi.org/10.5539/gjhs.v8n4p89

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Abstract

Background and Objective:Imbalance between oxidative stress and saliva antioxidants plays a major role in initiation and spread of dental caries. The aim of this study was to evaluate the total antioxidant capacity (TAC) of saliva in dental caries.Methods:In this case-control study which employed high school students (14-18 years), the un-stimulated saliva samples of 60 students without dental caries (control group) and 60 students with dental caries (with at least 5 teeth levels of dental caries) were gathered. Each group comprised of males (half of cases) and females (half of cases). TAC of saliva was measured by Zellbio® (Netherlands) in terms of micmol/L. The data were analyzed using the SPSS software (ver. 17.0) and t-test with considering significance level at 0.05.Results:TAC of saliva was significantly lower in cases with dental caries (0.256±0.106) compared to those without dental caries (0.396±0.077); P< 0.001. There was no statistically significant difference of TAC of saliva between males (0.319±0.119) and females (0.333±0.113) irrespective of dental caries (P=0.507).Conclusion:The results of the study indicated that there was a reverse association between dental caries and TAC of saliva.

Highlights

Dental caries is one the most common oral health disease and it's prevention is the important strategies in many countries (Hegde et al, 2009).Saliva is a complex fluid in the oral cavity, products by major and minor salivary glands and has the important role in oral health and specially prevention of dental caries (Lima et al, 2010; Mandel, 1993; Animireddy et al, 2014).Saliva composition, naturally or under certain conditions, varies in different individuals (Reyes et al, 2014)
total antioxidant capacity (TAC) of saliva was significantly lower in cases with dental caries (0.256±0.106) compared to those without dental caries (0.396±0.077); P< 0.001
The results of the study indicated that there was a reverse association between dental caries and TAC of saliva

Summary

Introduction

Dental caries is one the most common oral health disease and it's prevention is the important strategies in many countries (Hegde et al, 2009).Saliva is a complex fluid in the oral cavity, products by major and minor salivary glands and has the important role in oral health and specially prevention of dental caries (Lima et al, 2010; Mandel, 1993; Animireddy et al, 2014).Saliva composition, naturally or under certain conditions, varies in different individuals (Reyes et al, 2014). Saliva is a complex fluid in the oral cavity, products by major and minor salivary glands and has the important role in oral health and specially prevention of dental caries (Lima et al, 2010; Mandel, 1993; Animireddy et al, 2014). Total antioxidant capacity (TAC) is the total material in bodily fluids which possess antioxidant properties (Shafer et al, 2009). Saliva contains antioxidant similar to other bodily fluids. Imbalance between oxidative stress and saliva antioxidants plays a major role in initiation and spread of dental caries. The aim of this study was to evaluate the total antioxidant capacity (TAC) of saliva in dental caries

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Conclusion