Evaluation of tooth discoloration after the use of experimental medication as root canal dressings: an in vitro study.

Abstract

Endodontic infections require the use of root canal dressings to reduce microorganisms, and studies of new intracanal medications are common. Two experimental intracanal medications that contain antibiotics and chlorhexidine have been proposed. However, given the composition of these medications, tooth discoloration with subsequent impacts on aesthetic parameters is a concern. The objective of this study is to evaluate tooth discoloration after the use of experimental intracanal medications for up to 180 days. Thirty extracted bovine teeth were divided into 3 groups according to intracanal medication as follows: group I: experimental intracanal medication 1; group II: experimental intracanal medication 2; and group III: no medication (negative control). Color change was assessed using a spectrophotometer on day 0 (before the placement of the material); daily until the seventh day; and 8, 15, 60 and 180 days after removal of the medications. The values obtained were compared using ANOVA and Tukey's tests at a significance level of 5% (P<0.05). Up to 60 days after the removal of the medication, the teeth did not exhibit color changes. However, at 180 days, compared with the other medications, experimental intracanal medication 2 significantly promoted tooth staining (P<0.05). In contrast to experimental intracanal medication 2, intracanal medication 1 did not promote tooth discoloration.