Abstract
In the context of the above properties of titaniumaquacompleхglycerosolvate and oxytocin we have studied their joint application in order to increase the efficiency of treatment of soft tissue wounds. In the investigation performed, 144 experimental animals (white rats) with simulated aseptic wounds were studied. This study will contribute to develop a new treatment for soft tissue wounds, based on the application of aquaglitserosolvatetitanium and oxytocin, examine and assess the effectiveness of aquaglitserosolvatetitanium and oxytocin in the treatment of experimental soft tissue wounds. To assess the process of wound healing in the experiment, methods of clinical, planimetric progressive examinations of wounds, as well as strength characteristics of the scar formed were used. One of the objective measures of wound healing is the study of changes in the area in the healing process. The wound area was calculated by the method of L. N. Popovoy (1942). On the basis of clinical and planimetric methods of investigation, it was found that the decrease in the wound area is significantly faster under the influence of oxytocin and titanium aquacomplexglycerosolvate.
Highlights
IntroductionThe problem of treating wounds is one of the most important in surgery, being relevant to healthcare, because the outcome of wound healing and the patient’s work capacity depend on the effectiveness of its solution (Kuzin & Kostyuchenok, 1990; Datsenko, 1995; Adamyan & Glyantsev, 1992; Davydov & Larichev, 1999; Gostischev, 2003)
On the basis of studies conducted, it is found that the biological effect of titaniumaquacomplexglycerosolvate as an independent medication can be improved through an integrated application (Smagina & Beketov, 2006)
Experimental study was designed to study the effect of titaniumaquacomplexglycerosolvate and oxytocin on reparative processes in aseptic wounds of soft tissues
Summary
The problem of treating wounds is one of the most important in surgery, being relevant to healthcare, because the outcome of wound healing and the patient’s work capacity depend on the effectiveness of its solution (Kuzin & Kostyuchenok, 1990; Datsenko, 1995; Adamyan & Glyantsev, 1992; Davydov & Larichev, 1999; Gostischev, 2003). Local application of combinations of antibiotics with oxytocin significantly improved outcomes in patients with purulent-inflammatory diseases of soft tissues, with acute purulent diseases of lungs and pleura, with purulent sinusitis, in abdominal sepsis in the experiment (Kuzin, 1990). Analgesic properties of this hormone were discovered as early as in the 1970s (Bukharin, 1982)
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