Evaluation of the significance of intermediate coronary artery stenoses by stress perfusion CMR

James D Richardson,Angela G Bertaso,Payman Molaee,Kerry Williams,Benjamin K Dundon,Stephen G Worthley,Matthew I Worthley,Adam J Nelson,Karen S Teo,Dennis Wong,Hussam Tayeb

doi:10.1186/1532-429x-13-s1-p107

James D Richardson, Angela G Bertaso + Show 9 more

Open Access

https://doi.org/10.1186/1532-429x-13-s1-p107

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Abstract

Background A number of patients undergoing assessment for possible ischaemic heart disease proceed straight to coronary angiography without prior non-invasive functional tests. When an intermediate coronary lesion is then encountered, the functional significance of that lesion is often unclear. Invasive assessment with fractional flow reserve can clarify the situation but is not always available and involves significant expense. Non-invasive tests are then frequently requested to guide treatment. Adenosine stress perfusion imaging has been shown to have a high sensitivity and specificity for detecting ischaemic heart disease. We sought to determine the ability of stress perfusion CMR to guide management in these patients.

Highlights

A number of patients undergoing assessment for possible ischaemic heart disease proceed straight to coronary angiography without prior non-invasive functional tests
Evaluation of the significance of intermediate coronary artery stenoses by stress perfusion cardiac magnetic resonance (CMR)
Retrospective analysis of patients with an intermediate coronary stenosis on angiogram subsequently referred for adenosine stress CMR

Summary

Background

A number of patients undergoing assessment for possible ischaemic heart disease proceed straight to coronary angiography without prior non-invasive functional tests. When an intermediate coronary lesion is encountered, the functional significance of that lesion is often unclear. Invasive assessment with fractional flow reserve can clarify the situation but is not always available and involves significant expense. Non-invasive tests are frequently requested to guide treatment. Adenosine stress perfusion imaging has been shown to have a high sensitivity and specificity for detecting ischaemic heart disease. We sought to determine the ability of stress perfusion CMR to guide management in these patients

Methods

Results

Conclusions