Abstract
Aim: Investigating the potential role of prolactin in the prevention of diabetic retinopathy Methods: The study was conducted on 90 diabetic patients who were divided into a group that included 37 patients without retinopathy and a group that included 27 patients with non-proliferative retinopathy and 26 patients with proliferative retinopathy who attended the Endocrinology clinic and Division at Tishreen University Hospital in Lattakia during the period from 2023 to 2024. Results: Independent samples T-test analysis showed Significant decreased in prolactin level in diabetic patients with DR in comparison to diabetic patients without DR (p=0.0001). Person correlation showed a statistically significant inverse relationship between prolactin levels and Glycosylated hemoglobin levels between patient groups. Conclusions: From this study it can be concluded that diabetic patients with retinopathy had lower level of prolactin and serum prolactin does seem to have protective role in diabetic retinopathy.
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