Evaluation of the Respiratory Muscle Strength of Cirrhotic Patients: Relationship With Child-Turcotte-Pugh Scoring System

Abstract

Pulmonary abnormalities are observed in chronic hepatopathy. The measurement of the maximum inspiratory and expiratory pressure may evaluate lung function and the risks associated with hepatic transplantation. Thus, the present work sought to evaluate the respiratory muscle strength of 29 patients between 17 and 63 years old who were enrolled for liver transplantation. The patients were classified according to Child-Turcotte-Pugh score as A, B, or C, and also according to a physiotherapeutic evaluation, which included measurement of respiratory muscle strength by means of a digital manovacuometer, which determines the maximum inspiratory pressure (MaxIP) and the maximum expiratory pressure (MaxEP). The tests were performed with seated individuals having their nostrils obstructed by a nasal clip. The MaxIP was measured during the effort initiated in the residual volume, whereas the MaxEP was measured during the effort initiated in the total pulmonary capacity, keeping pressures stable for at least 1 second. The statistical analysis was performed through using the Mann-Whitney test with a 5% level of significance. The MaxIP values of Child A 95.5 ± 40.507 cm H 2O (average ± DP) and Child B 87.2 ± 35.02 patients were higher than those for Child C patients (34.83 ± 3.68; P < .05). Similar results were observed for the MaxEP of Child A and B groups (116.25 ± 31.98 and 97.28 ± 31.08, respectively; P < .05), versus the Child C group (48.16 ± 22.60). Between groups A and B, the MaxEP were similar ( P > .05). We concluded that Child C patients display muscle weakness significantly greater than that of subjects classified as Child A or B.