Abstract
Aim. The study of the prognosis of epidemiological and economic effects of pneumococcal vaccination in laboring males with various chronic diseases. Materials and methods. Within the predictive (Markov) model, based on the published data, assessment of 5-year horizon pneumococcal vaccination of laboring males perceived effectiveness in reducing mortality, avoiding morbidity and economic loss in the country had been processed. According to the official statistics in the Russian Federation 21 575 887 laboring males are within the high risk group for contracting pneumonia. Data source for the cost of the healthcare for disease had been the compulsory health insurance system 2016 state tariffs, for the vaccination cost results of the PCV13 procurement bidding had been used. Results. Data extrapolation from national and international studies to the cohort of individuals with chronic respiratory diseases, cardiovascular diseases and diabetes mel-litus vaccinated against pneumococcal infection showed a significant decrease in the risk of underlying diseases complications (OP=0,58, p
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