Abstract
OBJECTIVE: This study evaluated, in several analysis periods, pH and calcium release and antibacterial activity provided by MTA Fillapex sealer compared to Sealapex and AH Plus sealers. MATERIAL AND METHOD: Polyethylene tubes were filled with a sealer and immersed in distilled water. After 24 hours, 14 and 28 days, pH and calcium release by endodontic sealers were evaluated directly in water which the tubes were stored. Sealers antibacterial activity was evaluated against Enterococcus faecalis and Staphylococcus aureus by means of agar diffusion test. All data were submitted to ANOVA and Tukey tests (α=0.05). RESULT: In all periods evaluated, Sealapex had the highest pH value (p<0.05) in comparison to other sealers and MTA Fillapex provided higher pH values than AH Plus (p<0.05). In 14-days period, MTA Fillapex had greater calcium release value than Sealapex (p<0.05). In 28-days period, Sealapex provided higher calcium release than MTA Fillapex (p<0.05). In all periods, AH Plus provided lower calcium release than other sealers (p<0.05). In relation to E. faecalis, there were no differences among the sealers, in relation to antibacterial activity (p>0.05). In relation to S. aureus, Sealapex presented better antibacterial effectiveness than the MTA Fillapex and AH Plus (p<0.05), which were similar each other (p>0.05). CONCLUSION: In final evaluation period, pH values and calcium release provided by MTA Fillapex were lower than provided by Sealapex and higher than provided by AH Plus. The MTA Fillapex antimicrobial action was similar to other endodontic sealers.
Highlights
MATERIAL AND METHODMineral trioxide aggregate (MTA) is indicated to be used in root perforations, root-end cavities, for obturation of the apical portion of immature teeth, pulp capping, and pulpotomy[1]
The aim of this study was to evaluate pH and calcium release and antibacterial activity of METHODMineral trioxide aggregate (MTA) Fillapex sealer compared to AH Plus and Sealapex sealers
This study showed that MTA Fillapex provided high pH value and adequate calcium release during all periods evaluated and its antibacterial activity was similar to AH Plus, which is the endodontic sealer used as gold standard in endodontic material tests
Summary
Mineral trioxide aggregate (MTA) is indicated to be used in root perforations, root-end cavities, for obturation of the apical portion of immature teeth, pulp capping, and pulpotomy[1]. MTA-based sealers are biocompatible, stimulate mineralization[4], and exhibit higher push-out strengths than traditional oxide zinc and eugenol cement[5]. A new formulation of MTA-based cement (MTA Fillapex, Angelus Soluções Odontológicas, Londrina, PR, Brazil) was launched to be used as root canal sealer. Calcium hydroxide or calcium oxide-containing cements have been suggested as obturating materials because of their ability to dissociate into calcium and hydroxyl ions, resulting in a higher pH in the adjacent medium and inducing mineralized tissue formation[4,9]. Besides inducing mineralized tissue formation, another desirable property of root canal sealers is the antibacterial activity. The aim of this study was to evaluate pH and calcium release and antibacterial activity of MTA Fillapex sealer compared to AH Plus and Sealapex (new formulation) sealers
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