Evaluation of the optical quality of corneal spherical aberration-guided customized intraocular lens implants

Abstract

Objective To evaluate the optical quality of corneal spherical aberration-guided customized intraocular lens implants.Methods In a prospective study,64 age-related cataract patients (82 eyes) were selected for implantation of different spherical aberration intraocular lenses based on preoperative corneal spherical aberrations and measurements at the 6-mm pupil diameter (i-Trace).Patients were divided into four groups based on the predicted postoperative total spherical aberrations: group A:-0.15--0.05 μm (12 eyes),group B:-0.05-0.05 μm (24 eyes),group C:0.05-0.15 μm (25 eyes),group D: 0.15-0.5 μm (21 eyes).Uncorrected and best corrected visual acuity,wavefront aberration,MTF (modulation transfer function) curve and contrast sensitivity were measured 3 months after surgery.Data were analyzed with one-way ANOVA and paired t test.Results The total wavefront aberrations and higher order aberrations of group B and group C were much lower than that of group A and group D.There was a statistically significant difference among the four groups at spatial frequencies of 5,10,25,30 c/d of the MTF curve and in most contrast sensitivity spatial frequencies.And there was a statistically significant difference between group B and group C in contrast sensitivity spatial frequencies of 6.0,12.0,18.0 c/d (3 cd/m2,Glare).Conclusion Measurement of preoperative corneal spherical aberrations is helpful for selecting intraocular lenses.Corneal spherical aberration-guided customized intraocular lens implantation will be a new method for improving postoperative optical quality. Key words: Wavefront aberration, corneal; Intraocular lens ; Cataract ; Visual quality