Abstract

Magnesium gluconate is a classical organometallic salt used for the prevention and treatment of magnesium deficiency diseases. The objective of the current research was to explore the influence of The Trivedi Effect® - Energy of Consciousness Healing Treatment on the physicochemical, thermal and behavioral properties of magnesium gluconate using PXRD, PSD, FT-IR, UV-vis spectroscopy, TGA, and DSC analysis. Magnesium gluconate was divided into two parts – one part was control without any Biofield Energy Treatment, while another part was treated with the Biofield Energy Healing Treatment remotely by eighteen renowned Biofield Energy Healers and defined as the Biofield Energy Treated sample. The PXRD analysis exhibited significant alteration of the crystal morphology of the treated sample compared with the control sample. The crystallite size of the treated sample was remarkably changed from range -33.33% to 66.65% compared with the control sample. The average crystallite size was increased in the treated sample by 6.13% compared with the control sample. Particle size analysis revealed that the particle size at d10 value was significantly reduced in the treated sample by 13.20% compared with the control sample, although the particle size at d50 and d90 values were increased in the treated sample by 2.75% and 3.72%, respectively. The treated sample’s surface area was significantly enhanced (6.96%) compared with the control sample. The FT-IR and UV-vis analysis showed that the structure of magnesium gluconate remained similar in both the treated and control samples. The TGA analysis revealed that the weight loss of the first and second degradation steps in the treated sample was significantly decreased by 2.89% and 8.43%, respectively compared with the control sample, whereas at the third degradation step, the weight loss was enhanced by 14.80% compared with the control sample. The DSC analysis revealed that the melting point of the control and treated samples were 170.23°C and 170.25°C, respectively. The latent heat of fusion was significantly decreased by 6.15% in the treated sample compared with the control sample. The current study infers that The Trivedi Effect® - Energy of Consciousness Healing Treatment might lead to a new polymorphic form of magnesium gluconate, which could be more soluble and bioavailable compared with the untreated compound. Hence, the Biofield Energy Treated magnesium gluconate would be very useful to design better nutraceutical and/or pharmaceutical formulations that might offer better therapeutic responses against inflammatory diseases, immunological disorders, stress, aging and other chronic infections.

Highlights

  • Magnesium ion (Mg2+) is a major intracellular ion and plays an important role in the regulation of tRNA and rRNA structures

  • The Powder X-ray Diffraction (PXRD) analysis showed that the crystallite size of the Biofield Energy Treated magnesium gluconate was significantly changed in the range from 33.33% to 66.65% with respect to the control sample

  • The PXRD analysis indicated the alteration of the crystal morphology in the Biofield Energy Treated sample compared with the control sample

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Summary

Introduction

Magnesium ion (Mg2+) is a major intracellular ion and plays an important role in the regulation of tRNA and rRNA structures. Magnesium gluconate (MgC12H22O14) is the magnesium salt of gluconic acid It is used by itself or in combination with one or more antioxidants for the prevention and treatment of diabetes mellitus, allergies, septic shock, inflammatory diseases, immunological disorders, and other chronic infections [12, 13]. It can be used intravenously in the treatment of ischemia/reperfusion injury due to oxidative stress in order to block free radical flow [14]. Magnesium gluconate is one of the components in this novel proprietary herbomineral formulation as the source of magnesium

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