Evaluation of the Gram-Negative bacilli causing Surgical-Site infections and their sensitivity to antibiotics in Al-Mowasat Hospital, Damascus, Syria

Abstract

A Surgical-Site Infection (SSI) is an infection that occurs at a surgical cut within 30 days of a surgical operation. It is considered a major health issue in hospitals associated with high levels of morbidity and mortality. The infections caused by Gram-Negative Bacilli are main challenges to patients' health, because of high percentage of antibiotics resistance. This study aims to evaluate the incidence of SSIs in emergency surgical operations department, the epidemiology of Gram-Negative Bacilli in SSIs and their sensitivity to antibiotics. A total of 466 swab samples were taken from patients who had undergone surgical operations. Swabs were collected from the surgical incision or around it between December 2015 and March 2016. The results show the majority of bacterial isolates that cause the SSIs were Gram-Negative Bacilli (56%), while the Gram-Positive Cocci formed 44%, the predominant isolate was staphylococcus aureus (26/44) (59%) and the most commonly isolated Gram-Negative Bacilli were pseudomonas aeruginosa (22/56) (39.3%), followed by E.coli (14/56) (25%) and klebsiella (8/56) (14.4%). The most effective drugs were Imipenem and Meropenem followed by Amikacin.